Cellular and Molecular Mechanisms of Coronary Artery Spasm

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Editorial Comment Pathogenetic Mechanisms Coronary Artery Spasm*

Coronary artery spasm was first proposed as a cause of spontaneous, recurring angina1 attacks over a century ago (1). Because this brilliant clinical intuition could not be demonstrated at postmortem study, it fell into progressive disrepute until, in the early 1950s coronary artery spasm was considered “the resort of the diagnostically destitute” (2). In 1959, the notion of coronary artery spa...

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Multivessel coronary artery spasm.

A 60-year-old patient with variant angina was shown to have myocardial ischemia in two different regions supplied by separate major coronary arteries. Neither artery had significant coronary atherosclerotic obstruction. Ventricular fibrillation was noted during ST-segment elevation in anteroseptal leads. The attacks of pain and arrhythmias disappeared during nifedipine therapy.

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Coronary Artery Spasm

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ژورنال

عنوان ژورنال: Japanese Circulation Journal

سال: 2000

ISSN: 0047-1828,1347-4839

DOI: 10.1253/jcj.64.1